Isotopically Labeled Compounds
Medchemexpress LLC Triclocarban-d4 | 1219799-29-7 | 98.0% | 319.61 | C13H5D4Cl3N2O | 10 MG
Triclocarban-d4 is the deuterium-labeled analogue of triclocarban used as an analytical standard and internal tracer for quantitative LC-MS, GC-MS, and NMR analyses. It is supplied as a white to off-white solid intended for method development, quantitation, and metabolic or environmental studies.
- Deuterium-labeled internal standard for quantitative LC-MS and GC-MS.
- High purity (98.0%) suitable for analytical applications.
- Supplied as a 10 mg solid for analytical preparation.
- Stable isotope label enables accurate quantitation and tracer studies.
- Recommended storage: powder -20°C (3 years) or 4°C (2 years).
Medchemexpress LLC Mephenytoin-d5 | 1185032-66-9 | 98.7% | 5 MG
Mephenytoin-d5 is a deuterium-labeled version of Mephenytoin. Mephenytoin is an anticonvulsant and acts as a substrate for CYP2C19 and CYP2B6. This compound is intended for research use only.
- This compound can be used as a tracer.
- It can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements are incorporated into drug molecules for quantitation during the drug development process.
- Deuteration can impact the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Pyrimethanil-d5 | 2118244-83-8 | 99.0% | 1 MG
Pyrimethanil-d5 is the deuterium-labeled version of Pyrimethanil, an anilinopyrimidine and broad-spectrum contact fungicide. It controls Botrytis spp. on various crops by inhibiting the biosynthesis of methionine and other amino acids in *Botrytis cinerea*. It is suitable for research into fungal disease prevention in fruit, vegetable, and ornamental plants that have mold infections.
- Deuterium labeled compound.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes are incorporated for quantitation during drug development.
- Deuteration can affect the pharmacokinetic and metabolic profiles of drugs.
Sigma Aldrich Fine Chemicals Biosciences Urea-13C,15N2 99 atom % 13C, 98 atom % 15N | 58069-83-3 | MFCD00145506 | 500MG
Urea-13C,15N2 99 atom % 13C, 98 atom % 15N | Purity: 99% (CP) | Mol Wt: 63.03 | 58069-83-3 | MFCD00145506 | 500MG
Medchemexpress LLC Milnacipran-d10 hydrochloride | 1217774-40-7 | 99.9% | 1 MG
Milnacipran-d10 hydrochloride | 1217774-40-7 | 99.9% | 1 MG
Medchemexpress LLC Mefenamic Acid-d3 | 1189707-81-0 | 2.5 MG
Mefenamic Acid-d3 is the deuterium labeled Mefenamic acid. Mefenamic acid is a BBB-permeable non-steroidal anti-inflammatory agent, acting as a competitive inhibitor of hCOX-1 and hCOX-2, with IC50s of 40 nM and 3 μM, respectively. It can be used as a tracer or an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuterium labeled mefenamic acid
- BBB-permeable non-steroidal anti-inflammatory agent
- Acts as a competitive inhibitor of hCOX-1 and hCOX-2
- Suitable as a tracer for research
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Nadolol-d9 | 94513-92-5 | MFCD00049405 | 97.0% | 5 MG
Nadolol-d9 is a deuterium labeled Nadolol, functioning as a non-selective and orally active β-adrenergic receptors blocker. It is intended for research use only.
- Used as a tracer
- Functions as an internal standard for quantitative analysis
- Supports NMR, GC-MS, or LC-MS applications
Medchemexpress LLC Tilmicosin-d3 | 2714486-61-8 | 5 MG
Tilmicosin-d3 is the deuterium labeled Tilmicosin. Tilmicosin (LY-177370) is an orally active calcium channel antagonist and macrolide antibiotic with antimicrobial activity. It primarily acts on the 50S subunit of bacterial ribosomes, inhibiting protein synthesis.
- Effective in treating respiratory diseases in livestock such as cattle, sheep, and pigs.
- Possesses immunomodulatory and anti-inflammatory effects.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Clomipramine-d3 hydrochloride | 1398065-86-5 | 100.0% | 1 MG
Clomipramine-d3 (hydrochloride) is a deuterium-labeled variant of Clomipramine hydrochloride. Clomipramine hydrochloride functions as a blocker for the serotonin transporter (SERT), norepinephrine transporter (NET), and dopamine transporter (DAT), with Ki values of 0.14, 54, and 3 nM, respectively.
- Used as a tracer.
- Serves as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC 4,4'-((Pentane-1,5-diyl-1,1,5,5-d4)bis(oxy))dibenzimidamide dihydrochloride | 1276197-32-0 | 98.0% | 1 MG
Pentamidine-d4 dihydrochloride is the deuterium labeled Pentamidine dihydrochloride. It is an antimicrobial agent that interferes with DNA biosynthetics. This product appears as a white to off-white solid with a purity of 98.0% and an isotopic enrichment of 99.2%.
- Deuterium labeled compound
- Antimicrobial agent
- Interferes with DNA biosynthetics
- White to off-white solid
- Purity 98.0%
- Isotopic enrichment 99.2%
- Recommended storage at 4°C, sealed, away from moisture
- Recommended storage in solvent: -80°C for 6 months; -20°C for 1 month
Medchemexpress LLC Bicarbonate-13C sodium | 87081-58-1 | MFCD00084061 | 98.0% | 85.00 g/mol | NaH13CO3 | 1 G
Bicarbonate-13C sodium (NaH13CO3) is a 13C-isotope labeled sodium bicarbonate supplied as a stable-isotope tracer and analytical reference. It is provided with high chemical purity and documented physical data for use in research and analytical workflows.
- 13C-labeled sodium bicarbonate for tracer and analytical use.
- High purity suitable for NMR and mass spectrometry.
- Available in multiple package sizes, including 1 g.
- Provided with data sheet and safety data sheet for handling.
- Reliable molecular weight and formula information for calculations.
Medchemexpress LLC Acetylcholine-d9 chloride | 344298-95-9 | 99.0% | 1 MG
Acetylcholine-d9 chloride is a deuterium-labeled acetylcholine chloride, which is a potent, BBB-permeable cholinergic agonist. This neurotransmitter modulates the activity of dopaminergic neurons by stimulating nicotinic acetylcholine receptors and inhibits p53 mutant peptide aggregation in vitro. It can be utilized as a tracer or an internal standard for quantitative analysis through techniques like NMR, GC-MS, or LC-MS.
- Deuterium-labeled acetylcholine chloride
- Potent and BBB-permeable cholinergic agonist
- Modulates dopaminergic neuron activity
- Inhibits p53 mutant peptide aggregation in vitro
- Suitable as a tracer or internal standard for quantitative analysis
Medchemexpress LLC Tiopronin-d3 | 1189700-74-0 | 99.4% | 1 MG
Tiopronin-d3 is the deuterium labeled Tiopronin. Tiopronin acts as a diffusible antioxidant, an antidote to heavy metal poisoning, and a radioprotective agent. It can regulate the rate of cystine precipitation and excretion, showing potential for treating cystinuria, rheumatoid arthritis, and hepatic disorders. For research use only.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Candesartan-d4 | 1346604-70-3 | 98.2% | 1 MG
Candesartan-d4 (CV-11974-d4) is the deuterium labeled Candesartan, an orally active angiotensin II AT1-Receptor blocker and PPAR-γ agonist. It has potent and long-lasting antihypertensive effects and is used for the research of hypertension, chronic heart failure (CHF), and traumatic brain injury (TBI).
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Incorporates stable heavy isotopes into drug molecules for quantitation during drug development
- Deuteration can affect the pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Ipratropium-d7 bromide | 22254-24-6 | 1 MG
Ipratropium-d7 bromide is the deuterium-labeled form of Ipratropium bromide. Ipratropium bromide (Sch 1000) acts as a muscarinic receptor antagonist, with IC50 binding values of 2.9 nM for M1 receptors, 2 nM for M2 receptors, and 1.7 nM for M3 receptors. It is suitable for use in research related to COPD (chronic obstructive pulmonary disease) and asthma.
- This compound can be used as a tracer.
- It can serve as an internal standard for quantitative analysis through techniques such as NMR, GC-MS, or LC-MS.
- Stable heavy isotopes, including hydrogen, carbon, and other elements, have been integrated into drug molecules primarily for quantitation as tracers during drug development.
- Deuteration is recognized for its potential to influence the pharmacokinetic and metabolic profiles of drugs.